Exhibit 1

Joint Filing Agreement

The undersigned hereby agree that a single Schedule 13D (or any amendment thereto) relating to the Common Stock of OpGen, Inc. shall be filed on behalf of each of the undersigned and that this Agreement shall be filed as an exhibit to such Schedule 13D.

Dated: August 31, 2016

HARRIS & HARRIS GROUP, INC.

By: /s/ Daniel B. Wolfe                        

Name: Daniel B. Wolfe

Title: President

/s/ Daniel B. Wolfe                        

Daniel B. Wolfe

/s/ Douglas W. Jamison                        

Douglas W. Jamison